The best Side of cees dekker

The best Side of cees dekker

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Using one-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our study pursuits include things like:

You frequently get involved in conversations about science and faith. You may have also composed quite a few textbooks on the subject. Don’t you imagine that sooner or later We're going to know every little thing Which God’s purpose will likely be around?

[Laughs] ‘It had been undoubtedly a fantastic threat! At time, I was well aware that it could go wrong Which I could develop into a lot less productive, but I just dismissed that. Curiosity has usually been my strongest driving force. And fortunately everything labored out.’

Our operate was promptly adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.

This yielded a breakthrough. In just only a few months, we were being capable to evaluate transport as a result of someone one-walled carbon nanotube. Determined by reduced-temperature experiments by an excellent PhD student in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

You're a Christian. If you might make such a artificial cell, would you be just one phase closer to God, or would the job of God have diminished rather again?

Flow-driven rotary motors for example windmills and h2o wheels travel functional processes in human Culture. While samples of these types of rotary motors also function prominently in cell biology, their synthetic building with the nanoscale has remained complicated. Here we show circulation-driven rotary motion of the self-arranged DNA nanostructure that is definitely docked on to a nanopore in a thin strong-state membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the strong-state nanopore, and subsequently displays a sustained unidirectional rotary ceesdekker movement of up to twenty rev s−one.

2003, shown the 1st biosensors manufactured from a carbon nanotube; settled the structure and system of DNA repair service proteins; and discovery of a whole new approach for fabricating strong-point out nanopores for DNA translocation

Bulk-floor coupling identifies the mechanistic relationship concerning Min-protein patterns in vivo and in vitro

Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments

Character Physics thanks the nameless reviewers for their contribution to your peer overview of this get the job done.

Such as, we consider the nucleopore sophisticated, a gateway in between the mobile nucleus along with the cytoplasm. This is a very complicated process and so tough to research inside of a mobile, so we use biomimetics. We reconstruct holes and after that insert individual things in the nucleopore complex to review transport by it at the single-molecule amount.’

It had been an exceptionally interesting time, in the course of which I gained a lot of help from Delft College of Technological know-how, exactly where I used to be a professor at enough time, And that i begun a number of collaborations with molecular biologists. That assisted me study lots.’